INACTIVATION OF BACTERIOPHAGES BY DECAY OF INCORPORATED RADIOACTIVE PHOSPHORUS

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Inactivation of Bacteriophages by Decay of Incorporated Radioactive Phosphorus

The inactivation of the phages T1, T2, T3, T5, T7, and lambda by decay of incorporated P(32) has been studied. It was found that these phages fall into two classes of sensitivity to P(32) decay: at the same specific activity of P(32) in their deoxyribonucleic acid (DNA), T2 and T5 are inactivated three times as rapidly as T1, T3, T7, and lambda. Since the strains of the first class were found t...

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Inactivation of Bacteriophages by Decay of Incorporated Radioactive Phosphorus* by Gunther

I t was observed by Hershey, Kamen, Kennedy, and Gest (1951) that bacteriophages are unstable if they contain radiophosphorus p82 of high specific activity. From day to day, progressively decreasing fractions of such populations of radioactive phage are still able to form plaques when plated on a sensitive bacterial strain, and the rate of loss of infective titer depends on the specific activit...

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Inactivation of Bacteria by Decay of Incorporated Radioactive Phosphorus

Cultures of Escherichia coli will not grow in media containing very high specific activities of radiophosphorus P(32), the inhibition of growth being due to the decay of assimilated P(32) atoms. Experiments with a differentially labeled thymineless strain of E. coli show that the P(32) disintegrations which occur in the bacterial deoxyribonucleic acid, i.e. in the nucleus, are mainly responsibl...

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Inactivation of Bacteria by Decay of Incorporated Radioactive Phosphorus* by Clarence R. Fuerst$ and Gunther

Bacteriophages lose their infectivity upon decay of radiophosphorus Pn incorporated into their deoxyribonucleic acid (DNA). Each inactivation appears to be the consequence of the decay of a single atom of ps,, although only a fraction of such radioactive disintegrations is actually lethal. By means of reconstruction experiments it is possible to show that the ionizations produced by the hard Pn...

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Inactivation and mutations in Mycobacterium avium by decay of incorporated radioactive phosphorus.

NACTIVATION of bacteria and bacteriophages by decay of incorporated radio‘active phosphorus (P”) has been reported by STENT and FUERST (1955), FUERST and STENT (1956), STRAUSS, VAHARU, FRICKEY and MATHESON (1956), TESSMAN, TESSMAN and STENT (1957), MCFALL, PARDEE and STENT (1958), and KAUDEWITZ, VIELMETTER and FRIEDRICH-FREKSA ( 1958). These authors have suggested that the P32 disintegrations w...

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ژورنال

عنوان ژورنال: Journal of General Physiology

سال: 1955

ISSN: 1540-7748,0022-1295

DOI: 10.1085/jgp.38.4.441